Drugs currently used for treatment of PAH
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چکیده
منابع مشابه
Advanced therapies for the management of adults with pulmonary arterial hypertension due to congenital heart disease: a systematic review
Pulmonary arterial hypertension (PAH) secondary to congenital heart disease (CHD) is the third most common cause of PAH, and it is becoming increasingly common as improvements in the management of CHD have led to increased life expectancy for these patients. The medical management of PAH due to CHD (PAH-CHD) is largely the same as what has been used for the treatment of idiopathic PAH, though t...
متن کاملThe molecular targets of approved treatments for pulmonary arterial hypertension
Until recently, three classes of medical therapy were available for the treatment of pulmonary arterial hypertension (PAH)--prostanoids, endothelin receptor antagonists and phosphodiesterase type 5 (PDE5) inhibitors. With the approval of the soluble guanylate cyclase stimulator riociguat, an additional drug class has become available targeting a distinct molecular target in the same pathway as ...
متن کاملApoptosis-based therapy to treat pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is rare, but patients who are diagnosed with this disease still suffer from a lack of satisfactory treatment strategies to prolong survival. While currently approved drugs for PAH have some benefits, these vasodilators only have limited efficacy for eliminating pulmonary vascular remodeling and reducing mortality. Thus, our laboratory has been exploring the...
متن کاملCompelling evidence of long-term outcomes in pulmonary arterial hypertension? A clinical perspective.
Pulmonary arterial hypertension (PAH) is a rare and progressive disease of the pulmonary arterial circulation that is characterized by a progressive rise in pulmonary vascular resistance, eventually leading to right-heart failure and death. There are currently 3 classes of drugs approved for the treatment of PAH: prostacyclin analogues, endothelin receptor antagonists, and phosphodiesterase typ...
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Background: To present an overview of the pharmacologic treatment of pseudophakic macular edema. Methods: A systematic review of the currently accepted pharmacologic treatments for pseudophakic macular edema. Main outcome parameters include visual acuity and central macular thickness as determined by ocular coherence tomography. Articles retrieved by Pubmed search using keywords pseudophaki...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2011